DesignShop 11 and 12:
DesignShop 11 and DesignShop 12 are compatible with UHD 4K displays. To change the size of the icons in DesignShop v11, choose: Tools > Options... > Preferences > Icons and select your preferred icon size:
DesignShop v10:
DesignShop v10 will display very small icons on Ultra High Density (UHD) 4K displays. UHD 4K displays are not recommended for use with DesignShop v10, per the Melco System Requirements.
Microsoft Windows 10 does provide Compatibility Settings which may produce satisfactory display results.
It is recommended that you upgrade to DesignShop 12 for compatibility with UHD 4K Displays.